Human Papillomaviruses and Cervical Cancer: Biology and Immunology

This book is a review of HPV infection in cervical cancer and provides the background to the potential for immunological intervention. It will appeal to clinicians, virologists, cell and molecular biologists, and immunologists who are involved in the study of the molecular and biological basis for the role of HPV in cervical lesions.
Cervical cancer is a major disease worldwide, with 500,000 new cases diagnosed every year. Through aetiological studies, an association has been established with human papilloma virus (HPV) infection throughout the pathological spectrum of this disease. Studies of the molecular and biological basis for the role of HPV in cervical lesions involve clinicians, virologists, cell and molecular biologists, and most recently immunologists. This book is a review of HPV infection in cervical cancer, providing the background to the potential for immunological intervention. Individual chapters have been written so that the reader, irrespective of level or discipline, can follow the text, and each is integrated so that the book as a whole provides a detailed insight into the most relevant scientific issues of HPV and cervical cancer. This book should provide an interface for students, scientists and clinicians with a realistic and critical evaluation of the advances and problems in the implementation of immunologically based prophylactic and therapeutic strategies in HPV-associated disease.
This book should be of use to postgraduate students, research scientists and clinicians involved in eith