Mathematical, Computational and Experimental T Cell Immunology

The purpose of this book is to present current mathematical and computational models that are used to describe and characterise the immunology of T cells. The reader will be exposed to a variety of tools/methods that go hand-in-hand with the T cell-mediated immunological process that is being modelled.

We aim in the proposed book to emphasise the role that mathematical (or computational) modelling has already played in Immunology. Each chapter will provide an example of the contribution of mathematics to T cell immunology under one of the following four headings:

i) Generation of hypotheses,

ii) Quantification of immunological processes,

iii) Definition of observables to measure given an experimental objective,

iv) reconciling disparate (or even conflicting) experimental results.