Metal Toxicology Handbook

Heavy metals and metalloids, singly or in combination, induce their toxic manifestations either through acute or chronic pathology. In particular, long-term chronic exposure to diverse heavy metals and metalloids to humans and animals can lead to numerous physical, muscular, neurological, nephrological and diverse degenerative diseases and dysfunctions including multiple sclerosis, muscular dystrophy, Parkinson's and Alzheimer's diseases, cardiovascular disorders and several others.

Recognized heavy metals such as lead, mercury, arsenic, cadmium, thallium and hexavalent chromium are known for enormous toxicity. The immediate vital signs of acute heavy metal exposure include nausea, vomiting, diarrhea and acute abdominal pain. Mercury has been identified as the most toxic heavy metal and mercury poisoning is known as acrodynia or pink disease. Similarly, lead, another toxic heavy metal, used to be an integral part of painting.

The Metal Toxicology Handbook further explains and discusses the varying attributes of metals, discussing toxicity, safety and proper human utilization of metals. Beginning with a broad overview of metals, metalloids, redox biology and neurodegeneration and going further into the roles, benefits, and toxicity of metals with each section, this text contains 28 chapters from eminent researchers and scientists in their field and is a must have anyone researching the potential toxicity in metals.

　

Key Features:

Discusses pathology of metal toxicity

Highlights the benefits of metals

Explains the mechanism and salient features of restoring metabolic homeostasis

Highlights dose-dependent beneficial and adverse effects of vanadium safety and toxicity

The initial Introduction section provides a broad overview on metals, metalloids, redox biology & neurodegeneration. The second section discusses the pathology of metal toxicity in two chapters, while the third section highlights the mechanism and salient features of restoring metabolic homeostasis in two dedicated chapters. The fourth section demonstrates the aspect on radionuclides toxicity. In a change of pace, the fifth section discusses the benefits of metals in four individual chapters. The sixth section entitled "Toxic Manifestations by Diverse Heavy Metals and Metalloids" provides fourteen chapters that discuss the toxicological mechanism and manifestation of individual metals.

The Editors crafted a Commentary entitled "A Treatise on Metal Toxicity" and summarizes a vivid scenario of metal toxicity and its consequences.