Particulate Interactions in Dry Powder Formulation for Inhalation

Interactions between drug particulates are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles and factors in pharmaceutical powder technology, reviews some of the studies in dry powder formulation development, and proposes strategies for improving their efficiency.
Interactions between drug particulate are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles established in surface and colloidal chemistry with pharmaceutical powder technology. It discusses some of the factors affecting particulate interactions, and particle-fluid interaction in the respiratory tract. It critically reviews some of the studies carried out in dry powder formulation development, and proposes possible strategies in improving DPI efficiency. The majority of these principles are applicable to other pharmaceutical solid dosage forms.